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Hypertrophic osteodystrophy


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#1 aphillippi

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Posted 24 March 2010 - 02:45 PM

Does anyone have any experiece with this? My 5 month old Crunchy has just been diagnosed with it. He has been having horrible pain in all four legs and had a fever. It started last week and I took him to the vet. They put him on an antibiotic and said if he wasn't feeling better in a few days to bring him back for more testing. He did great over the weekend playing like his normal self and all then Monday he started having problems walking again.

They did x-rays and a slew of blood work. We won't get the results on the blood work until the end of the week. She is pretty sure Crunchy has HOD and is hoping it will be a mild case. I've work for vets and seen a lot of things I've had a dog with Addison's Disease. I'm just really freak out about this and what it is going to do to him. It just broke my heart watching my labx slowly wither away and having to make the decision to let her go. But she was older and this is just breaking me up considering he is only 5 months old.

#2 BustopherJones

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Posted 24 March 2010 - 02:56 PM

What kind of dog is Crunchy? HOD is usually found in young large breed dogs.
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#3 aphillippi

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Posted 24 March 2010 - 02:59 PM

So I've been told. He is a full blooded border collie.

#4 eclare

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Posted 01 April 2010 - 10:43 AM

I'm kind of afraid that this is what is wrong with Seamus. We're going to the vet next week.
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#5 Dobbin

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Posted 17 March 2011 - 01:08 PM

Our dog Jack is a Border Collie and is going throught HOD as well. He had his first occurance in September 2010. It put him in the hospital for 4 days/nights the first time and 4 days/night a month later. He is still having them about every 4 weeks now. They are not as bad anymore but we were wondering how long you dealt with the HOD. It feels like it is never going to go away.

#6 mjk05

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Posted 18 March 2011 - 06:02 AM

I know a couple of people who have had sheepdog breed pups with HOD (border collies and NZ Heading Dog-collie cross). They were all large pups who grew to be big adults, and while I think they had a hard time for a while it was all good in the end. One of my pups was diagnosed with HOD after a couple of admissions to a specialist vet centre at 4-5 months, but unfortunately it turned out that he actually had TNS. Fingers crossed for your pup- HOD usually has a pretty good prognosis, even if it's horrible at the time.

#7 Dobbin

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Posted 05 November 2011 - 09:31 AM

I know a couple of people who have had sheepdog breed pups with HOD (border collies and NZ Heading Dog-collie cross). They were all large pups who grew to be big adults, and while I think they had a hard time for a while it was all good in the end. One of my pups was diagnosed with HOD after a couple of admissions to a specialist vet centre at 4-5 months, but unfortunately it turned out that he actually had TNS. Fingers crossed for your pup- HOD usually has a pretty good prognosis, even if it's horrible at the time.



Our Border Collie Jack was originally diagnosed with HOD but now a specialist thinks after a bone marrow biopsy that he has TNS. We don't know what to do now. Jack is 18 months and is sick every 3-4 weeks. When do we say enough is enough. Is he suffering, is his quality of life what it should be? This is the hardest thing I have ever dealt with. Any advice?

#8 Journey

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Posted 05 November 2011 - 10:21 AM

Have you sent in a sample to USW to test him for TNS? Or have you gone through optigen? Either one can tell you his genetic statis for TNS. What is the pedigree on Jack?
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#9 Dobbin

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Posted 05 November 2011 - 10:29 AM

Have you sent in a sample to USW to test him for TNS? Or have you gone through optigen? Either one can tell you his genetic statis for TNS. What is the pedigree on Jack?


Jack is a pure breed American standard Border Collie. We have not sent samples away. This is all very new to the vets here in Toronto, Canada. That is why the vet can't give a 100% diagnoses. The breeder we got Jack from has sent samples away to be tested. She should hear back in about 2 weeks. Jack shows all the symptoms. It is very sad when he is sick but when he is not sick he is a crazy border collie. I guess we should get a test ordered and sent away.

#10 Journey

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Posted 05 November 2011 - 01:31 PM

If he's TNS affected he's one of the longest living ones tbomk. I'd tend to doubt TNS but as far as a diagnosis goes there's only one way to answer that difinitively. Genetic test him.
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#11 rushdoggie

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Posted 05 November 2011 - 01:50 PM

I'm sorry, I haven't. My puppy had pretty severe pano so I can sympathize, though this seems much more serious. Is the x ray a definitive diagnosis?

One thing I learned is that a dog in pain during adolescence can have an effect on his temperament and if I were in your shoes pain management would be high on the list of things to address.

Good luck.

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#12 Dobbin

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Posted 05 November 2011 - 02:04 PM

If he's TNS affected he's one of the longest living ones tbomk. I'd tend to doubt TNS but as far as a diagnosis goes there's only one way to answer that difinitively. Genetic test him.


The diagnosis on the vets report say Chronic Neutropenia. They have found that the neutrophil is not leaving the bone marrow. Like I mention before the vet is almost certain it is TNS. I think our next step needs to be a swab. We need to know for sure. Our poor puppy is sick right now. His symptoms right now are no appetite, sore throat, fever, lethargic and he threw up two times this week. It is so heart breaking.

#13 Journey

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Posted 05 November 2011 - 02:54 PM

Either way it's nasty and I'm sorry your Jack is so sick. Have you shared this with your vet. http://bordercollieh...NSdatabase.html and the study attached to it from Dr. Wilton? If it is TNS it's something that needs to be brought to the attention if the health committees in the US & Canada.
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#14 Liz P

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Posted 05 November 2011 - 04:12 PM

Definitely let us know if a TNS test (DNA) comes back positive. If so, he would be the first working dog I've ever heard of that is affected. Can you share his pedigree?

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#15 Journey

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Posted 05 November 2011 - 06:03 PM

Thanks for catching that Liz, just because he's american bred doesn't mean he's "working" bred. Dobbin, can you clarify? Is he AKC/CKC registered how far back can you go in his pedigree? Any imports from KC registries? Or is he truly "working/farm" bred?
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#16 Dobbin

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Posted 05 November 2011 - 06:40 PM

I am a rookie when it comes to pedigrees and such. I am a suburban Border Collie owner! I do know that we do not have Jack's paperwork because we have not got Jack fixed. He has been too sick. He is from Hollowshot Border Collies in Hastings, Ontario, Canada. The breeder is now waiting for results for the TNS tests. She will know in 2 weeks.

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#17 Journey

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Posted 05 November 2011 - 06:59 PM

Dobbin, thank you. If you don't mind me really being a pest....we might be able to help you pedigree wise! Who are the sire & dam of your Jack? Do you recall?
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#18 Dobbin

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Posted 05 November 2011 - 07:06 PM

Dobbin, thank you. If you don't mind me really being a pest....we might be able to help you pedigree wise! Who are the sire & dam of your Jack? Do you recall?



The sire is Hollowshot Mill Reef and the dam is Hollowshot Tibbie. I have that information!

#19 Journey

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Posted 05 November 2011 - 07:17 PM

Oh Dobbin, thank you and I'm sorry. Your Jack very well could have TNS. He's not a working bred pup, he's a show bred pup. With the genetic testing available in this day and age there is absolutely no excuse for producing affected offspring. I wish you and Jack the best. Please do keep us posted about Jack. I wish you the best and agree with him not being neutered!
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#20 grenzehund

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Posted 05 November 2011 - 07:35 PM

What a sweet-looking pup! So sorry he's suffering; you're doing right to get all the information you can and just loving him. We'll be sending positive thoughts.

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